New Potential Therapeutic Target – FFA4 Protein – Discovered for COPD

New Potential Therapeutic Target – FFA4 Protein – Discovered for COPD
Evidence of a new potential therapeutic target — a protein called free fatty acid receptor 4 (FFA4) — in the treatment of inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) has been found in a new study. The study, "Pathophysiological regulation of lung function by the free fatty acid receptor FFA4," was published in the journal Science Translational Medicine. FFA4 is normally found in the gut and pancreas and is activated by dietary fats such as omega-3 fatty acids, typically present in fish. Once activated in these tissues, FFA4 works to help control blood glucose levels. The protein also is abundant on the epithelial cells of the lungs, a previous study showed.  Meanwhile, a more recent study suggested that omega-3 fatty acid activation of FFA4 might be beneficial in lung tissue repair. However, no further data is available regarding the molecule's potential role in the lungs. Now, an international team led by researchers at the University of Glasgow, in the U.K.,
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