A blood test to measure levels of the immune signaling protein interleukin-32 (IL-32) may be a useful biomarker to diagnose and assess the severity of chronic obstructive pulmonary disease (COPD), a new study suggests. The study, “…
News
Evidence of a new potential therapeutic target — a protein called free fatty acid receptor 4 (FFA4) — in the treatment of inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) has been found in a new study. The study, “Pathophysiological…
Verona Pharma has started the second part of a Phase 2 trial evaluating its investigational therapy ensifentrine (RPL544) in patients in the U.K. with moderate to severe chronic obstructive pulmonary disease (COPD), following delays related to COVID-19, the company announced in a press release. Part…
Researchers at Washington University School of Medicine in St. Louis have been awarded $3.9 million in funding to continue developing a treatment candidate that reduces mucus production and inflammation in debilitating lung diseases, such as chronic obstructive pulmonary disease (COPD) and asthma. The award from the…
PR1P, a small peptide able to increase the activity of vascular endothelial growth factor (VEGF) in cells lining the inside of blood vessels, can reduce lung cell death and tissue damage in a mouse model of emphysema, a study reports. According to investigators, these findings highlight the therapeutic…
Adhering to a healthy diet — be it a Mediterranean diet, a prudent diet, or a diet supported by health associations — significantly lowers the risk of chronic obstructive pulmonary disease (COPD), a recent meta-analysis suggests. Unhealthy diets, such as the Western diet, appear to…
To help people experiencing the lingering effects of coronavirus infection, the Pulmonary Wellness Foundation (PWF) has launched a free online rehabilitation and recovery program called COVID Bootcamp 101. In addition to patient education and support, the program offers breathing and other exercises conducted by a team of…
AstraZeneca‘s Breztri Aerosphere has been approved by the U.S. Food and Drug Administration (FDA) as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Formerly known as PT010, Breztri Aerosphere is an inhaled therapy with three active components: the long-acting muscarinic antagonist…
Patients with chronic obstructive pulmonary disease (COPD) should be more cautious when taking metformin, a common medication used to treat diabetes. In patients with both COPD and type 2 diabetes mellitus (T2DM), metformin carries a higher risk for pneumonia, hospitalization for COPD, and invasive mechanical ventilation. This…
Younger patients report feeling a heavier burden and greater daily impact from the symptoms of chronic obstructive pulmonary disease (COPD) than older patients, a global survey has revealed. Physicians should thus optimize treatment for these younger patients, say researchers leading the survey. The findings were published in an article,…
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