News

Seebri Neohaler, a long-term maintenance therapy for airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), is now available at U.S. pharmacies. “COPD is a serious, progressive respiratory disease that should have a personalized approach to choosing a therapy and delivery method,” Dr. Edward Kerwin, medical director of the…

E-cigarettes are not at all beneficial for chronic obstructive pulmonary disease (COPD) patients trying to quit smoking or to mitigate the health consequences of nicotine, according to a new study. The study reporting the findings was published in the Journal of General Internal Medicine and is titled “…

Researchers from the Imperial College London in England and the National University of Singapore (NUS) have identified a grape polyphenol, known as isorhapontigenin, which shows potential for suppressing lung inflammation caused by chronic obstructive pulmonary disease (COPD). The naturally-derived compound belongs to the family of polyphenols, which are found abundantly…

The AIRWISE phase 4 clinical trial aiming to assess how commonly prescribed medicines may decrease the worsening of symptoms in chronic obstructive pulmonary disease (COPD) has begun enrolling the first patients. The AIRWISE trial (NCT03265145) is described as the world’s largest ever pragmatic clinical trial,…

AstraZeneca’s Bevespi Aerosphere was shown to improve lung function in patients with moderate- to very severe-chronic obstructive pulmonary disease (COPD), in the latest PINNACLE 4 clinical trial. The promising results pave the way for regulatory approval in Europe and Asia. Bevespi Aerosphere combines two bronchodilators, glycopyrronium (long-acting…

Stem cells offer protective effects for damaged lung cells exposed to cigarette smoking by alleviating oxidative stress in mitochondria, a study shows. These results were also observed in mice and suggest a potential new therapeutic strategy for oxidative stress-dependent lung diseases, such as chronic obstructive pulmonary disease (COPD). The study…

Synairgen is moving from the treatment of respiratory viral infections in patients with asthma to those with chronic obstructive pulmonary disease (COPD) with its inhaled interferon beta investigative therapy SNG001. The pharmaceutical company is planning a two-part trial of SNG001 to treat viral infections in COPD patients to take place this…

Verona Pharma’s lead investigational medicine RPL554, engineered to treat patients with chronic obstructive pulmonary disease (COPD) and other respiratory disorders, was found to have an effective therapeutic profile when administrated by inhalation to healthy volunteers. This finding resulted from data obtained during a U.S. clinical trial that Verona…

The U.S. Patent and Trademark Office (USPTO) issued two new patents requested by Pulmatrix – one for the expansion of its iSPERSE drug delivery technology and one for the expansion of protections for PUR0200, the company’s investigative candidate for chronic obstructive pulmonary disease (COPD). iSPERSE technology delivers drugs directly…

Two Phase 3 clinical trials demonstrated that the antibody Nucala (mepolizumab) from GlaxoSmithKline has a moderate efficacy in the reduction of the rate of exacerbations in chronic obstructive pulmonary disease (COPD) patients. The almost 20 percent decrease in the exacerbation rate was only observed in COPD patients with high levels of…