Apria Healthcare has started a program to help COPD patients get the most out of mechanical ventilation by not only having respiratory therapists train them but also visit their homes to make sure they’re using it correctly. The Apria Clinical Evidence, or ACE, program is aimed at improving the healthcare outcomes…
Verona Pharma recently announced clinical development updates and interim results for the first half of 2017 for RPL554 as a treatment for chronic obstructive pulmonary disease (COPD) with the start of four new clinical trials. Verona developed RPL554 as a nebulized dual-inhibitor of the enzymes phosphodiesterase 3 and 4…
The European Union has approved Trimbow as a maintenance treatment for adults with moderate to severe chronic obstructive pulmonary disease. Trimbow, developed by Italy’s Chiesi Group, is the first triple-combination inhaler for COPD. It contains the inhaled corticosteroid beclometasone dipropionate, the β2 agonist formoterol fumarate, and the muscarinic antagonist glycopyrronium.
Verona Pharma recently dosed the first patients in its Phase 2b clinical trial evaluating RPL554 as a maintenance treatment for chronic obstructive pulmonary disease (COPD). RPL554 is a first-in-class dual inhibitor of the enzymes phosphodiesterase 3 and 4. The drug has anti-inflammatory and bronchodilator properties. An inhaled formulation of…
A vaccine that Novavax developed to deter the virus that causes most lung infections generated the desired immune response in children, and was safe, according to clinical trials. The trials dealt with the RSV F vaccine’s ability to protect older adults and children from the respiratory syncytial virus, or RSV. The…
Results of a Phase 3 trial of the investigational drug revefenacin (TD-4208) for the treatment of moderate to very severe chronic obstructive pulmonary disease (COPD) demonstrated the therapy is well tolerated and is associated with a lower incidence of adverse side effects compared to standard of care with Boehringer Ingelheim’s…
Severe cases of chronic obstructive pulmonary disease (COPD) can lead to structural changes in the lungs. These changes not only aggravate lung function, they can also alter the bacterial community (microbiome) that reside in the lungs, according to the results of a study published in the journal PLOS ONE.
Sunovion Pharmaceuticals will divest its U.S. market rights for ciclesonide products for the treatment of asthma and allergic rhinitis to Covis Pharma. With this agreement, Sunovion confirms its focus on chronic obstructive pulmonary disease (COPD), and continued development of treatment options for this condition. Sunovion’s ciclesonide products (a type of…
Cytokinetics recently launched a Phase 1b clinical trial designed to evaluate the effect of CK-2127107 on physical function in older adults with limited mobility due to diseases associated with muscular weakness and/or fatigue, including chronic obstructive pulmonary disease (COPD). The therapeutic candidate is a next-generation fast skeletal muscle troponin activator…
Although studies show that continuous positive airway pressure (PAP) therapy can reduce hospitalizations among patients with chronic obstructive pulmonary disease (COPD), less than 8 percent of patients receive this treatment. PAP is a treatment delivered by a device that gently forces pressurized room air through the airways to keep the…
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