News

Topline Results Reported in Pilot Study for COPD Therapy

Pulmatrix recently reported topline results from a Phase 1 pilot study evaluating PUR0200, an iSPERSE dry powder formulation incorporating a marketed long-acting and once daily bronchodilator, as a therapy for chronic obstructive pulmonary disease (COPD). Under collaborative terms and with support from the pharmaceutical company Mylan, Pulmatrix headed the pharmacokinetic…

Opioid Use in Older COPD Patients Can Worsen Prognosis

Treating older adults with chronic obstructive pulmonary disease (COPD) with opioids may not be the best idea. Researchers at St. Michael’s Hospital, in Toronto, Canada, have shown that new opioid users have up to five times higher risk of death than non-opioid users. The findings were published recently in the…

Cytokinetics Begins Phase 2 Study of Therapy for COPD Patients

San Francisco-based biopharma Cytokinetics initiated a Phase 2 clinical trial to evaluate the effect of CK-107 on physical function in patients with chronic obstructive pulmonary disease (COPD). CK-2127107 (CK-107) is a novel fast skeletal muscle troponin activator under development as a potential therapy for COPD, spinal muscular atrophy (SMA), and other conditions. It…

COPD Improves with Stem Cell Therapy

Four Lung Institute facilities in Tampa, Scottsdale, Nashville and Pittsburg, treat restrictive and obstructive lung diseases using stem cells from the patient’s own body. Gary V., a patient, has seen his quality of life improve since he receive stem cell therapy for chronic obstructive pulmonary disease (COPD). For Gary, “improvement” is…

Triple Combination Therapy Shows Promise in COPD; Superior to Symbicort/Turbohaler Therapies

GlaxoSmithKline and Innoviva announced positive data from the Phase 3 FULFIL clinical trial evaluating their investigational triple combination therapy with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/IV) in patients with chronic obstructive pulmonary disease (COPD). FULFIL is a randomized, double-blind, multicenter study designed to evaluate the efficacy and safety of a daily dose of the FF/UMEC/IV…