AERO-007 — a combination of two classes of bronchodilators delivered via a standard jet nebulizer — led to rapid and clinically meaningful improvements in lung function among adults with moderate-to-severe chronic obstructive pulmonary disease (COPD). That’s according to data from the Phase 2a portion of a Phase 1/2a…
Discussion
When I learned that pilot Chuck Yeager grew up with his family name spelled Jeager, something in me paused. The story goes that when he joined the military, no one could understand how to spell it. He kept repeating himself, trying to explain the German “J” that sounds…
Discussion
Some symptoms arrive with fanfare — a cough that won’t settle, a flare that tightens the chest, a night when the oxygen just doesn’t feel like enough. But others slip in quietly. Lately, I’ve been having days when my temperature rises just a little above normal. Not a true fever,…
Discussion
When I was a young girl, I had a hen named Wimpy. She got her name because she had a game leg and limped when she walked, but that limp never slowed her determination. Wimpy laid 12 eggs and rolled them, one by one, to her nest. Then she settled…
Discussion
When I was a little girl, my mother often sent me to the cornfield with my father. I suspect it was partly to give her a moment of quiet, because I was at the age of endless questions. Daddy didn’t mind. He handed me a hoe and gave me a…
One year of treatment with tozorakimab, AstraZeneca’s experimental therapy, was reported to significantly reduce the annual rate of moderate-to-severe exacerbations, or periods of sudden symptom worsening, in adults with chronic obstructive pulmonary disease (COPD). These are the top-line results from the global Phase 3 MIRANDA clinical trial (NCT06040086),…
COPD is a chronic inflammatory disease of the lungs, in which the airways become blocked, causing cough with mucus, wheezing, and shortness of breath.
The causes of COPD are not fully understood. However, long-term exposure to lung irritants is known to damage the lungs and the airways.
Some people may also experience exacerbations, or episodes of sudden disease worsening, that may persist for several days.
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