Author Archives: Margarida Maia PhD

Astegolimab Lifts Quality of Life For Those With Frequent Flare-ups

Patients with moderate-to-very severe chronic obstructive pulmonary disease (COPD) and frequent flare-ups who were given astegolimab, a medicine in Genentech’s pipeline, reported a better health-related quality of life than those taking a placebo, a study found. The findings are from a Phase 2a trial, called COPD-ST2OP (NCT03615040),…

First COPD Patient Enrolled in Phase 4 Study of Yupelri vs. Spiriva

A first patient has been enrolled in a Phase 4 study of the effectiveness of Yupelri (revefenacin) against Spiriva (tiotropium) in improving lung health in adults with severe chronic obstructive pulmonary disease (COPD). The respective safety of these two approved, once-daily COPD maintenance treatments will also be evaluated. Yupelri, developed…

Anti-inflammatory Compound MgIG Eases COPD Symptoms in Rat Model

An anti-inflammatory compound used in China to help treat liver disease — known as magnesium isoglycyrrhizinate (MgIG) — eased the symptoms of chronic obstructive pulmonary disease (COPD) by reducing inflammation in the lungs, a study in a rat disease model reported. “These findings suggest MgIG might be an alternative for…

Simple, Low-cost Tests May Help Identify Undiagnosed COPD in China

Low-cost screening involving a questionnaire and a breathing test may help identify patients with undiagnosed chronic obstructive pulmonary disease (COPD), a study conducted in China has found. Among the combinations tested, the Chinese symptom-based questionnaire (C-SBQ) combined with microspirometry — a test that measures how much air a patient…

Hemoglobin May Be Promising Biomarker of Clinical Outcomes

Hemoglobin, the protein that carries oxygen in blood, may be a promising biomarker to assess the clinical outcomes of patients with chronic obstructive pulmonary disease (COPD), a large U.S.-based study has found. The findings indicate that unusually high or low levels of hemoglobin were linked to worse clinical outcomes.

Study Pushes for Better Dental Care in Brazil for COPD Patients

Dental care in Brazil needs to be more accessible to patients with chronic obstructive pulmonary disease (COPD) and integrated into their primary care to better tackle the impact of the disease in the country, a study suggests. “Our research indicates that incorporating preventative oral health into COPD management and…