Author Archives: Diogo Pinto

Age, Mechanical Ventilation, Disease Severity Influence Hospital Mortality in COPD Patients, Study Says

A 10-year study has identified several factors that are independent predictors of hospital mortality in critically ill patients with severe chronic obstructive pulmonary disease (COPD). These factors include a patient’s age, the need for mechanical ventilation, and disease severity, the study shows. The research, titled “Factors associated with hospital…

PUR0200 Shown to Be as Good as Spiriva HandiHaler for COPD in Phase 1 Trial

Pulmatrix‘s branded generic of Spiriva HandiHaler, called PUR0200, was shown to promote similar improvements in lung function in patients with chronic obstructive pulmonary disease (COPD), but at significantly lower doses than Spiriva, according to a Phase 1 clinical trial. The study reporting the findings is titled “The pharmacokinetics,…

Genome of Dangerous Pathogen Deciphered in 15-year Study of COPD Patients

A 15-year study demonstrated how nontypeable Haemophilus influenzae (NTHi), one of the most important pathogens in chronic obstructive pulmonary disease (COPD), adapts and survives in patients’ airways over time. The research findings were reported in the journal Proceedings of the National Academy of Sciences, in a study titled “…

Long-term Aspirin Use Reduces Severity of Acute COPD Exacerbations, Study Reports

The long-term use of aspirin was found to reduce the severity of acute exacerbations in chronic obstructive pulmonary disease (AECOPD), including in-hospital mortality, invasive ventilation use, and hospital length-of-stay (LOS), researchers reported. The study, “The association of aspirin use with severity of acute exacerbation of chronic obstructive pulmonary disease:…