Lindsey Shapiro PhD, science writer —

Therapeutic Solutions International (TSOI) reported discovering a new mechanism of action for JadiCell, its investigative stem cell therapy for chronic obstructive pulmonary disease (COPD) and other conditions. Working in animal models, scientists found that JadiCell’s protective effects were dependent on certain immune B-cells and a signaling molecule…

Chronic obstructive pulmonary disease (COPD) was associated with an increased risk of overall mortality, as well as higher chances of cardiovascular, respiratory, and cancer-associated deaths, in a group of people living in Finland, a recent study has found. While asthma was also linked to a higher mortality risk over…

Mortality rates associated with chronic obstructive pulmonary disease (COPD) were declining in men but rising among women in many countries as of 2019, according to a recent study. This shift is likely related to changes in smoking habits, with smoking generally declining in men but being more variable among…

Despite treatment, a large number of people with chronic obstructive pulmonary disease (COPD) in the U.S. continue to experience a high symptom burden and frequent exacerbations, or episodes of sudden disease worsening, a study reported. Findings highlight the need to better understand the real-world effectiveness of COPD management strategies…

Researchers have developed a device to prevent shortness of breath in people with chronic obstructive pulmonary disease (COPD) and other chronic lung conditions. When breathing through the hands-free device, called PEP Buddy, the user’s exhales are prolonged, resulting in slower breathing rates and preventing breathlessness. “There are many…

Immune responses to COVID-19 vaccination were similar in people with chronic obstructive pulmonary disease (COPD) to those of healthy adults, a U.K. study found. “The results of this study will be a great relief for patients with COPD who can rest assured they can derive protection from COVID-19 vaccination,…

Poor sleep significantly increased the risk of disease flare-ups in current or former smokers with chronic obstructive pulmonary disease (COPD), a study found. “Sleep has not been extensively studied as a modifier of COPD outcomes,” Marishka Brown, PhD, director of the National Heart, Lung, and Blood Institute’s (NHLBI) National…

Treatment with immune-suppressing myeloid-derived suppressor cells alongside JadiCell — an investigational stem cell therapy from Therapeutic Solutions International (TSOI) for chronic obstructive pulmonary disease (COPD) — led to more significant reductions in lung damage in mice compared with either treatment alone. Using them together also enhanced pulmonary regeneration…

Therapeutic Solutions International (TSOI) is seeking permission from the U.S. Food and Drug Administration (FDA) to conduct a Phase 1 study of JadiCell, its investigational stem cell therapy, in 10 people with advanced chronic obstructive pulmonary disease (COPD). The request — submitted in the form of an investigational…