News

Urine test may predict COPD exacerbations 1 week in advance

A urine test developed in a dipstick format by Global Access Diagnostics helped not only distinguish between stable and exacerbation states among chronic obstructive pulmonary disease (COPD) patients but also was able to predict exacerbations a week in advance. That’s according to the results of a new study…

Lung inflammation in COPD is reduced with a form of vitamin B3

Oral supplementation with nicotinamide riboside, a form of vitamin B3, helped reduce markers of lung inflammation in older adults with chronic obstructive pulmonary disease (COPD), data from a placebo-controlled study shows. The benefits were sustained for at least three months after supplementation ended. These findings are “significant, because inflammation…

Ohtuvayre effective across key patient subgroups: ENHANCE trials

Ohtuvayre (ensifentrine), an inhaled therapy approved in the U.S. earlier this year for adults with chronic obstructive pulmonary disease (COPD), has been found to safely and effectively lead to clinical improvements among COPD patients regardless of disease severity, smoking history, and chronic bronchitis history. Chronic bronchitis is a…

FDA approves Dupixent for adults with poorly controlled COPD

The U.S. Food and Drug Administration (FDA) has approved Dupixent (dupilumab) as an add-on maintenance treatment for adults with poorly controlled chronic obstructive pulmonary disease (COPD) and high counts of immune cells called eosinophils. Elevated eosinophils are a marker of type 2 inflammation, which is thought to contribute…

Voice changes may enable early detection of COPD exacerbations

The voice of people with chronic obstructive pulmonary disease (COPD) becomes more pitched and sounds breathy or hoarse at the early stages of disease exacerbations, which are episodes when symptoms suddenly worsen, according to a pilot study where 28 patients were asked to record their voices every day for…

Mepolizumab reduces exacerbations in COPD with type 2 inflammation

Adding GSK’s mepolizumab to standard inhaled treatment reduces the frequency of moderate to severe exacerbations in chronic obstructive pulmonary disease (COPD) patients with type 2 inflammation, which contributes to lung inflammation. That’s according to top-line data from a Phase 3 clinical trial called MATINEE (NCT04133909) announced by GSK…