News

Immune-suppressing Cells Boost JadiCells’ Therapeutic Effects in Mice

Treatment with immune-suppressing myeloid-derived suppressor cells alongside JadiCell — an investigational stem cell therapy from Therapeutic Solutions International (TSOI) for chronic obstructive pulmonary disease (COPD) — led to more significant reductions in lung damage in mice compared with either treatment alone. Using them together also enhanced pulmonary regeneration…

TSOI Seeks FDA OK to Launch Phase 1 Trial of JadiCell

Therapeutic Solutions International (TSOI) is seeking permission from the U.S. Food and Drug Administration (FDA) to conduct a Phase 1 study of JadiCell, its investigational stem cell therapy, in 10 people with advanced chronic obstructive pulmonary disease (COPD). The request — submitted in the form of an investigational…

New Tool Better Predicts Risk of COPD in Ethnically Diverse Groups

Researchers have developed a new genetic tool for predicting the risk of chronic obstructive pulmonary disease (COPD) in individuals of non-European ancestry. It was found to more effectively determine COPD risk for both African Americans and heavy smokers than existing models that are primarily built on genetic information from…

In Lung Cancer Patients, COPD Tied to More Surgery Complications

Among people with lung cancer who undergo tumor removal surgery, chronic obstructive pulmonary disease (COPD) is linked to a higher rate of postoperative pulmonary complications and longer hospital stays, including a greater need for intensive care unit (ICU) treatment, according to a large retrospective Australian study. A history of…

Lung Signaling Protein ISM1 May Be New COPD Therapeutic Approach

Lung-directed treatment with isthmin 1 (ISM1) — a soluble signaling molecule naturally present in the lungs — reduced lung inflammation, suppressed emphysema development, and preserved lung function in a mouse model of chronic obstructive pulmonary disease (COPD), a study shows. Emphysema is a severe form of COPD marked by damage…

FDA OKs World’s First Infrasound Stethoscope in US

The U.S. Food and Drug Administration (FDA) will allow Sanolla’s VoqX to be used in the clinic, the first stethoscope that can be used to detect infrasounds — acoustic waves that humans cannot hear. The primary care stethoscope — a diagnostic tool clinicians normally use to listen to sounds…