News

Nuvaira, a medical device company, announced it has secured $79 million to support the AIRFLOW-3 clinical trial to assess the company’s new targeted lung denervation (TLD) system, a minimally invasive treatment for chronic obstructive pulmonary disease (COPD). COPD includes a group of diseases characterized by chronic airway obstruction…

The first generic version of the inhalation treatment Advair Diskus (fluticasone/salmeterol powder) was recently approved by the U.S. Food and Drug Administration for chronic obstructive pulmonary disease (COPD) and asthma patients. According to a press release from developer Mylan, the therapy, called Wixela Inhub (fluticasone propionate and salmeterol inhalation powder),…

People with chronic obstructive pulmonary disease (COPD) have an increased risk of severe illness, hospitalization, and death if they become infected with the influenza virus, according to a Canadian study. Researchers emphasize that getting a flu vaccine can significantly reduce these risks. The study, published in the journal…

Physicians at Illinois’ Northwestern Memorial Hospital are the first in the United States to successfully perform a robotic-assisted lung volume reduction surgery (LVRS) to extract diseased tissue from the lungs of patients with severe emphysema, a progressive form of chronic obstructive pulmonary disease (COPD). The first procedure was done in late…

Data from a three-day Phase 2 clinical trial offered positive results for nebulized ensifentrine (RPL544) as an add-on treatment for chronic obstructive pulmonary disease (COPD), its developer Verona Pharma announced. Ensifentrine is an inhibitor of phosphodiesterase (PDE) proteins PDE3 and PDE4, which are involved in smooth muscle contraction and immune cell-derived inflammation, respectively.

Exosomes — tiny vesicles used for cell communication, released from specific activated immune cells called polymorphonuclear leukocytes — can induce chronic obstructive pulmonary disease (COPD) when transferred to the lungs of healthy mice, a study by researchers at the University of Alabama at Birmingham (UAB) shows. The study, “Activated PMN exosomes: Pathogenic…

Verona Pharma’s investigational agent RPL554 will be named ensifentrine, the company announced. The “-fentrine” stem in the International Nonproprietary Names (INN) Programme indicates recognition from the World Health Organization (WHO) that RPL554 inhibits multiple phosphodiesterases. Ensifentrine is being developed for the maintenance treatment of chronic obstructive pulmonary disease (COPD)…