Nighttime COPD Symptoms Impact Activities, Quality of Life: Survey

Nighttime breathing symptoms related to chronic obstructive pulmonary disease (COPD) significantly impaired daily activities and health-related quality of life, a survey of patients and physicians revealed. Most of the surveyed patients (74%) reported having nocturnal symptoms, while physicians reported that they prescribed treatments based on 24-hour symptom relief for…

Pollution, Distance From Green Spaces Tied to Quality of Life

The health-related quality of life of people with chronic obstructive pulmonary disease (COPD) living in Barcelona, Spain, is negatively affected by exposure to air pollution and living farther away from green or blue water-rich spaces, a study suggests. “This study, performed for the first time on a Mediterranean population,…

Mepolizumab Lessens Exacerbations, Improves Quality of Life

Treatment with mepolizumab, an antibody designed to lower the levels of eosinophils — immune cells linked with worse chronic obstructive pulmonary disease (COPD) — was found to reduce the annual rate of exacerbations and improve health-related quality of life in people with eosinophil-associated COPD. The findings, from a meta-analysis…

Nebulized Ensifentrine Shows Promise as Add-on Therapy

Verona Pharma has announced positive efficacy and safety results about using nebulized ensifentrine as an add-on therapy to tiotropium (Spiriva Respimat) for treating symptomatic chronic obstructive pulmonary disease (COPD). Results from the Phase 2b clinical trial (NCT03937479) show that ensifentrine treatment, combined with maintenance tiotropium, results in…