Margarida Maia, PhD,  science writer—

The first patient has been dosed in a Phase 2a clinical trial testing ReAlta Life Sciences’ RLS-0071 in adults with chronic obstructive pulmonary disease (COPD) who are experiencing acute exacerbations, or sudden symptom worsening. The trial (NCT06175065) will evaluate the safety of RLS-0071 versus a placebo in…

A Phase 2a clinical trial of AstraZeneca’s experimental therapy mitiperstat is now recruiting adults with moderate to severe chronic obstructive pulmonary disease (COPD) at a study site in Choctaw, Oklahoma. The Care Access research site is among nearly 20 study centers in the U.S., located across 11…

Pulmonary (lung) rehabilitation nearly halves the odds of people with chronic obstructive pulmonary disease (COPD) experiencing an exacerbation, and it also cuts the risk of dying by about one-third, a study in Korea found. The study, “Pulmonary Rehabilitation Is Associated With Decreased Exacerbation and Mortality in Patients With…

The number of people worldwide with chronic obstructive pulmonary disease (COPD) is predicted to increase by 23% in three decades, amounting to nearly 600 million patients by 2050, according to a new study. The largest increase, by nearly 50%, is projected to be among women and people living in…

The U.S. Food and Drug Administration (FDA) has agreed to review Verona Pharma’s application seeking approval of inhaled ensifentrine as a maintenance treatment for chronic obstructive pulmonary disease (COPD). FDA’s review team now has up to 10 months to examine all data filed with the new drug…

Lupin Pharmaceuticals has penned a deal with low-cost pharmacy Mark Cuban Cost Plus Drugs and the COPD Foundation to broaden access for patients in the U.S. to a generic option of an approved tiotropium bromide dry inhalation powder for chronic obstructive pulmonary disease (COPD). Used with the…

People who take inhaled corticosteroids for their chronic obstructive pulmonary disease (COPD) may be at lower risk for developing certain cardiovascular diseases, a review study has found. The study, “Inhaled Corticosteroids and Risk of Cardiovascular Disease in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Regression,”…

Many African Americans with clear symptoms of chronic obstructive pulmonary disease (COPD) don’t get a formal diagnosis because current diagnostic tools might not work as well for them, a study finds. Lung structure differences among African Americans that result in scores higher than the cutoff used to diagnose COPD…

A first person with chronic obstructive pulmonary disease (COPD) has been dosed with ensifentrine, an inhaled medication in the pipeline of Verona Pharma, as part of a Phase 3 clinical trial that recently opened in China. The trial, called ENHANCE China (NCT05743075), is evaluating the efficacy…

People with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) may experience fewer acute disease exacerbations if they regularly use noninvasive ventilation at night, a small study in Greece reported. “Good” nighttime use of continuous positive airway pressure (CPAP), a type of noninvasive ventilation, also aided lung…