A protein called ABCC1 lets a specific signaling molecule leak out of muscle cells in the airways, which may contribute to the airway constriction that makes it harder for people with asthma or chronic obstructive pulmonary disease (COPD) to breathe, a recent study reported. “This protein has been recognized…
Seven days of treatment with ensifentrine, given using a pressurized metered-dose inhaler — called a pMDI — resulted in marked lung function improvements in people with moderate to severe chronic obstructive pulmonary disease (COPD), according to data from a Phase 2 clinical trial. “This study demonstrates that ensifentrine administered…
A mucus protein called MUC5AC may contribute to the abnormally thick and sticky mucus that develops in people with respiratory diseases such as chronic obstructive pulmonary disease (COPD), a new study shows. “MUC5AC seems to be crucial to the formation of stagnant, thicker mucus we see in pulmonary…
Two additional Blue Cross Blue Shield (BCBS) plans are now covering Pulmonx’s Zephyr Endobronchial Valve and similar devices to treat severe emphysema, a form of chronic obstructive pulmonary disease (COPD). With the addition of these two plans to similar previous policy decisions, valves will be now covered for the…
Renovion is teaming up with the COPD Foundation to develop a new nebulized therapy that aims to help clear mucus and reduce inflammation in people with chronic obstructive pulmonary disease (COPD) and non-cystic fibrosis bronchiectasis. Phase 2 clinical trials of the investigational treatment, called  ARINA-1, are planned to…
Noninvasive ventilation at home, known as NIVH, can reduce the risk of hospitalization, emergency department visits, and death in people with chronic obstructive pulmonary disease (COPD) who have trouble getting enough oxygen, new research indicates. NIVH is a breathing support technique given at home, using a face or nasal…
A $12.8 million five-year renewal grant from the National Institutes of Health (NIH) will fund research that seeks to better understand the molecular mechanisms that drive chronic obstructive pulmonary disease (COPD) and other lung diseases. The research also aims to increase understanding of how cigarette smoking affects the development…
Treatment with PRP-PC, an investigational platelet-based cellular therapy, may slow the decline in lung function typically experienced by people with chronic obstructive pulmonary disease (COPD), a new study with real-world data indicates. With this therapy, being developed by H-CYTE, a person’s own blood is treated in the lab…
The Zephyr Endobronchial Valve significantly improved lung function and quality of life for at least two years in people with emphysema, a severe form of chronic obstructive pulmonary disease (COPD), according to new clinical trial data. “These long-term data further demonstrate that our Zephyr Valve is a safe,…
Enrollment is now concluded in a clinical trial evaluating the mechanism of action of RejuvenAir Metered Cryospray, an investigational treatment for chronic bronchitis, the most common form of chronic obstructive pulmonary disease (COPD). Chronic bronchitis is long-term inflammation of the airways, characterized by coughing and excessive mucus production.
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