Marisa Wexler, MS, senior science writer —

The U.S. Food and Drug Administration (FDA) has issued a warning letter to AstraZeneca for making false or misleading claims about Breztri Aerosphere (budesonide/glycopyrronium/formoterol fumarate), its approved inhalation therapy for chronic obstructive pulmonary disease (COPD). According to the FDA, promotional material about Breztri distributed by AstraZeneca includes claims…

Verona Pharma has filed an application asking the U.S. Food and Drug Administration (FDA) to approve inhaled ensifentrine as a maintenance treatment for chronic obstructive pulmonary disease (COPD). The regulatory submission “is a significant milestone towards our goal of bringing this potential first-in-class therapy to COPD patients…

People with chronic obstructive pulmonary disease (COPD) tend to experience worsening symptoms at times when levels of pollution in their community are higher, a new U.S. study indicates. “Our findings are consistent with a growing number of studies reporting adverse effects of community-level exposure to air pollution on respiratory…

Prompt treatment with Breztri Aerosphere (budesonide/glycopyrronium/formoterol fumarate) after a moderate or severe chronic obstructive pulmonary disease (COPD) exacerbation can lower the risk of a future worsening episodes. That’s according to data by AstraZeneca, which markets Breztri Aerosphere, in the late-breaking abstract, “Exacerbations and Real-world Outcomes…

Among people with chronic obstructive pulmonary disease (COPD) who have emphysema, individuals who continue to smoke after being diagnosed tend to have faster progression of lung damage, a recent study reported. According to researchers, these findings imply quitting smoking may help slow lung disease progression. “We were able to…

Many people with chronic obstructive pulmonary disease (COPD) or asthma use their inhaler therapies incorrectly, according to a recent study conducted at a center in Turkey. “The misuse of inhalers has been an obstacle to both patients and clinicians for many years and unfortunately still remains a significant issue,”…

Ensifentrine, an inhaled treatment being developed by Verona Pharma, lowered the rate of exacerbations, or episodes of sudden disease worsening, across all subgroups of patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) in the Phase 3 ENHANCE-2 trial. “We are very encouraged by the meaningful and consistent reductions…

Most people with chronic obstructive pulmonary disease (COPD) who participated in a U.S. pilot program of NuvoAir’s virtual monitoring service reported a decrease in hospitalizations and a better quality of life, the company announced. NuvoAir’s COPD solution uses proprietary home monitoring devices, including a spirometer and an…

An experimental anti-inflammatory medication called DMX-700, being developed by Dimerix for chronic obstructive pulmonary disease (COPD), was found to substantially reduce lung injury in a mouse model of the disease. “DMX-700 has demonstrated some very encouraging pre-clinical data,” Nina Webster, PhD, CEO and managing director of Dimerix,…

Levels of a protein called LOXL1 are elevated in the lungs of people who smoke cigarettes, as well as in those with chronic obstructive pulmonary disease (COPD), a recent study reported. According to researchers, these findings highlight the importance of LOXL1 and similar proteins in disease processes associated with…