Author Archives: Patricia Inacio PhD

Exosomes Released by Immune Cells Can Cause COPD, Study Finds

Exosomes — tiny vesicles used for cell communication, released from specific activated immune cells called polymorphonuclear leukocytes — can induce chronic obstructive pulmonary disease (COPD) when transferred to the lungs of healthy mice, a study by researchers at the University of Alabama at Birmingham (UAB) shows. The study, “Activated PMN exosomes: Pathogenic…

FDA Asks GSK for More Evidence of Mepolizumab’s Ability to Help Treat Flares in COPD Patients

GlaxoSmithKline’s application for approval of mepolizumab as an add-on therapy to reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD) requires more clinical data, the U.S. Food and Drug Administration (FDA) said in a complete response letter. GSK sought approval for mepolizumab as an add-on to inhaled corticosteroid-based maintenance treatments used…

Switch to Electronic Cigarettes May Help COPD Patients, Study Reports

Electronic cigarettes help reduce exacerbations and improve exercise capacity in patients with chronic obstructive pulmonary disease (COPD) who saw their condition get worse by smoking conventional cigarettes, a new study reports. The study, “Health effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up” was…