News

Grants Awarded to Gut Microbiome, Influenza Research in Australia

Researchers at the Centenary UTS Centre for Inflammation in Australia have been awarded grants to investigate potential therapeutics for respiratory conditions like chronic obstructive pulmonary disease (COPD). One of the awards is a $5-million National Health and Medical Research Council (NHMRC) Synergy Grant that will investigate methods in…

Antioxidant NAC Found to Ease Lung Scarring in Preclinical Study

Treatment with the antioxidant N-acetylcysteine (NAC) lowered blood levels of pro-inflammatory molecules and reduced lung scarring, or fibrosis, in a rat model of chronic obstructive pulmonary disease (COPD), a study shows. This beneficial effect was associated with the suppression of two molecules — von Willebrand factor (VWF) and p38 mitogen-activated…

Treatment With pMDI Ensifentrine Found to Improve Lung Function

Seven days of treatment with ensifentrine, given using a pressurized metered-dose inhaler — called a pMDI — resulted in marked lung function improvements in people with moderate to severe chronic obstructive pulmonary disease (COPD), according to data from a Phase 2 clinical trial. “This study demonstrates that ensifentrine administered…

Hemoglobin May Be Promising Biomarker of Clinical Outcomes

Hemoglobin, the protein that carries oxygen in blood, may be a promising biomarker to assess the clinical outcomes of patients with chronic obstructive pulmonary disease (COPD), a large U.S.-based study has found. The findings indicate that unusually high or low levels of hemoglobin were linked to worse clinical outcomes.

MUC5AC Protein May Help Cause Thick, Sticky Mucus in Lungs

A mucus protein called MUC5AC may contribute to the abnormally thick and sticky mucus that develops in people with respiratory diseases such as chronic obstructive pulmonary disease (COPD), a new study shows. “MUC5AC seems to be crucial to the formation of stagnant, thicker mucus we see in pulmonary…

Repeat Lung Injury Depletes Stem Cell Pool There, May Promote COPD

Repeated lung injury increases the biological age of lung stem cells and progressively diminishes their regenerative abilities, according to a study in mice and lab-grown human cells. These findings suggest that such repeat damage contributes to the abnormal repair and tissue remodeling that characterizes chronic obstructive pulmonary disease (COPD) and…

Zephyr Valve Now Covered By 2 More Blue Cross Blue Shield Plans

Two additional Blue Cross Blue Shield (BCBS) plans are now covering Pulmonx’s Zephyr Endobronchial Valve and similar devices to treat severe emphysema, a form of chronic obstructive pulmonary disease (COPD). With the addition of these two plans to similar previous policy decisions, valves will be now covered for the…