Sporting the color orange and “lacing up” for patients, supporters nationwide are participating in COPD Awareness Month, observed each November to call attention to the lung disorder that affects nearly 16 million U.S. residents, with millions more undiagnosed. World COPD Day is Nov. 17. Awareness and education are crucial…
A protein called ABCC1 lets a specific signaling molecule leak out of muscle cells in the airways, which may contribute to the airway constriction that makes it harder for people with asthma or chronic obstructive pulmonary disease (COPD) to breathe, a recent study reported. “This protein has been recognized…
Female nurses who worked in operating rooms (ORs) for 15 years or more are up to 69% more likely to develop chronic obstructive pulmonary disease (COPD) than those who never served in an OR, according to a large-scale study from the Boston University School of Public Health (BUSPH). Causing…
Researchers at the Centenary UTS Centre for Inflammation in Australia have been awarded grants to investigate potential therapeutics for respiratory conditions like chronic obstructive pulmonary disease (COPD). One of the awards is a $5-million National Health and Medical Research Council (NHMRC) Synergy Grant that will investigate methods in…
Treatment with the antioxidant N-acetylcysteine (NAC) lowered blood levels of pro-inflammatory molecules and reduced lung scarring, or fibrosis, in a rat model of chronic obstructive pulmonary disease (COPD), a study shows. This beneficial effect was associated with the suppression of two molecules — von Willebrand factor (VWF) and p38 mitogen-activated…
Seven days of treatment with ensifentrine, given using a pressurized metered-dose inhaler — called a pMDI — resulted in marked lung function improvements in people with moderate to severe chronic obstructive pulmonary disease (COPD), according to data from a Phase 2 clinical trial. “This study demonstrates that ensifentrine administered…
Hemoglobin, the protein that carries oxygen in blood, may be a promising biomarker to assess the clinical outcomes of patients with chronic obstructive pulmonary disease (COPD), a large U.S.-based study has found. The findings indicate that unusually high or low levels of hemoglobin were linked to worse clinical outcomes.
The National Institutes of Health (NIH) has awarded a five-year grant to a Yale researcher to support his work on the molecular and cellular mechanisms underlying emphysema, a severe form of chronic obstructive pulmonary disease (COPD). The R01 grant, titled “Role of MIF and CD74 in the pathogenesis…
Artificial intelligence (AI) is becoming ubiquitous in all areas of life — used in the houses people live in and the cars they drive, and in the smartphones used every day to post updates on social media. But now AI is making inroads into the nonprofit world, with the…
A mucus protein called MUC5AC may contribute to the abnormally thick and sticky mucus that develops in people with respiratory diseases such as chronic obstructive pulmonary disease (COPD), a new study shows. “MUC5AC seems to be crucial to the formation of stagnant, thicker mucus we see in pulmonary…
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