Treatment with human mesenchymal stem cells (MSCs) results in a strong, but temporary, reduction in pro-inflammatory molecules involved in chronic obstructive pulmonary disease (COPD), according to data from a Phase 1 clinical trial involving nine COPD patients. Notably, molecules directly produced by MSCs were identified as potential drivers of these…
News
Kaleido Biosciences is teaming up with the COPD Foundation to investigate KB109, a small compound designed to modulate the gut microbiome — the community of microbes living in the intestines — as a potential treatment for chronic obstructive pulmonary disease (COPD). The decision was based on promising…
One hundred patients have been randomly assigned in Nuvaira’s pivotal AIRFLOW-3 clinical trial that will investigate the efficacy and safety of targeted lung denervation (TLD) to reduce exacerbations, or episodes of symptom worsening, of chronic obstructive pulmonary disease (COPD) in patients on optimal medical care. Because of the…
Life in the wake of the COVID-19 pandemic isn’t the only “new normal.” Wildfires in the northwestern U.S. and Canada have become regular summertime occurrences in the northern hemisphere, with more than half of U.S. states being affected by the particulate matter that blows over from the fires, according to…
Smaller particles and optimal inhalation speed of inhaler treatments — a mainstay for people with chronic obstructive pulmonary disease (COPD) — enhance their delivery to deep airway passages, a study shows. The study, “Computational evaluation of drug delivery in human respiratory tract under realistic inhalation,” was…
GoodRx, a platform for healthcare savings in the U.S., and pharmaceutical company Boehringer Ingelheim have teamed up to help lower out-of-pocket medication costs for people with chronic obstructive pulmonary disease (COPD) or type 2 diabetes. Patients will be able to enroll in sponsored copay programs to access Boehringer…
Treatment with mepolizumab, an antibody designed to lower the levels of eosinophils — immune cells linked with worse chronic obstructive pulmonary disease (COPD) — was found to reduce the annual rate of exacerbations and improve health-related quality of life in people with eosinophil-associated COPD. The findings, from a meta-analysis…
COPD SOS, a public service campaign spearheaded by veteran broadcast journalist Ted Koppel and his wife, is aimed at identifying the millions of people who don’t yet know that they have chronic obstructive pulmonary disease (COPD). This disease is estimated to affect 30 million people in the U.S.,…
Injecting mice with healthy lung endothelial cells — specialized cells lining the inside of blood vessels — prevented, and in some cases reversed, lung damage associated with emphysema, a severe form of chronic obstructive pulmonary disease (COPD), in a recent study. The study, “Reversal of emphysema…
The Zephyr Endobronchial Valve leads to sustained and significant improvements in lung function, exercise capacity, and quality of life in people with homogeneous emphysema, a severe form of chronic obstructive pulmonary disease (COPD), according to one-year data from the IMPACT clinical study. “This is very important data because…
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