The U.S. Food and Drug Administration (FDA) accepted for review a New Drug Application (NDA) submitted by Theravance Biopharma and Mylan for their collaborative compound revefenacin (TD-4208), a bronchodilator for the treatment of chronic obstructive pulmonary disease (COPD) in adults. The two pharmaceutical companies are aiming to develop and…
AstraZeneca’s Daliresp (roflumilast) is now approved at 250 micrograms (mcg) for the first four weeks followed by 500 mcg thereafter to treat patients with chronic obstructive pulmonary disease (COPD). This approval by the U.S. Food and Drug Administration (FDA) will help reduce the rate of discontinuation previously reported in patients…
Better and more adequate home-based care for patients with chronic obstructive pulmonary disease (COPD) can significantly improve their quality of life and reduce the need of hospital-based treatments. This finding was reported by the Canadian Foundation for Healthcare Improvement (CFHI) as a result of its INSPIRED initiative,…
Variations in the anatomy of airway branches may be used as indicators for people at higher risk of developing chronic obstructive pulmonary disease (COPD), a new study found. The team of researchers, funded by the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH), discovered…
A new class of kinase inhibitors shows promising anti-inflammatory effects in airway cells of patients with chronic obstructive pulmonary disease (COPD), according to a collaborative research study. The study, “Superior anti-inflammatory effects of narrow-spectrum kinase inhibitors in airway smooth muscle cells from subjects with chronic obstructive…
ResMed has introduced Mobi, a portable oxygen concentrator for people with chronic respiratory diseases. Oxygen therapy is the most important non-drug component of the treatment of patients with chronic obstructive pulmonary disease. San Diego-based ResMed said Mobi, which is lightweight and has a good battery life, will go on sale in…
Zinc deficiency in the lung causes overproduction of mucus and is associated with respiratory diseases such as chronic obstructive pulmonary disease (COPD), a new Japanese study shows. The research study, “Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in…
Patients with chronic obstructive pulmonary disease (COPD) carry much higher levels of glucose in their airways, increasing the growth of bacteria and consequently the risk of infections, according to researchers from Imperial College London. Their study, “Role of airway glucose in bacterial infections in patients with chronic obstructive…
A diet rich in fresh tomatoes and fruits, especially apples, slowed the natural decline of lung function over a 10-year period among former smokers, found a study by Johns Hopkins Bloomberg School of Public Health in Baltimore. In fact, these foods can help slow down the decline of lung function for…
The U.K.’s National Institute for Health and Care Excellence (NICE) has updated its guidelines to include endobronchial valves as an appropriate routine treatment for severe emphysema, an advanced form of chronic obstructive pulmonary disease (COPD). This announcement comes on the heels of positive safety and effectiveness data from multiple…
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