Pulmonary (lung) rehabilitation nearly halves the odds of people with chronic obstructive pulmonary disease (COPD) experiencing an exacerbation, and it also cuts the risk of dying by about one-third, a study in Korea found. The study, “Pulmonary Rehabilitation Is Associated With Decreased Exacerbation and Mortality in Patients With…

No matter how well I plan or how much I want to do something, I have to remember that my chronic obstructive pulmonary disease (COPD) is in control. One such reminder happened two weeks ago, as I was rounding up suitcases, securing a driver, and ensuring my house sitter…

A combination of antibiotics may be more effective at killing harmful bacteria in the lungs of people with chronic obstructive pulmonary disease (COPD) who are having disease exacerbations, or flare-ups, than single-antibiotic therapies, a study based on a trial’s findings reports. However, the study found no difference between combination…

Treatment with mepolizumab, an antibody designed to lower the levels of eosinophils — immune cells linked with worse chronic obstructive pulmonary disease (COPD) — was found to reduce the annual rate of exacerbations and improve health-related quality of life in people with eosinophil-associated COPD. The findings, from a meta-analysis…

Nuvaira’s targeted lung denervation (TLD) therapy lowers the risk of hospitalization due to exacerbations in people with chronic obstructive pulmonary disease (COPD), Phase 2 trial data show, according to a company press release. A new clinical study, called AIRFLOW-3 (NCT03639051), is currently recruiting COPD patients at multiple…

Long-term use of low-dose macrolide antibiotics is safe and potentially effective in reducing acute exacerbations in younger patients with chronic obstructive pulmonary disease (COPD) who are at risk for poorer outcomes, a review study suggests. Although this therapeutic regimen was found to be generally well-tolerated, with few side effects,…

Add-on treatment with asthma medication Fasenra (benralizumab) failed to reduce annual exacerbations in patients with moderate to very severe chronic obstructive pulmonary disease (COPD), according to final results of two Phase 3 trials. Findings were reported in the study, “Benralizumab for the Prevention of COPD Exacerbations,”…

The AIRWISE phase 4 clinical trial aiming to assess how commonly prescribed medicines may decrease the worsening of symptoms in chronic obstructive pulmonary disease (COPD) has begun enrolling the first patients. The AIRWISE trial (NCT03265145) is described as the world’s largest ever pragmatic clinical trial,…

Two Phase 3 clinical trials demonstrated that the antibody Nucala (mepolizumab) from GlaxoSmithKline has a moderate efficacy in the reduction of the rate of exacerbations in chronic obstructive pulmonary disease (COPD) patients. The almost 20 percent decrease in the exacerbation rate was only observed in COPD patients with high levels of…

Chiesi recently completed a long-term study showing that its extra-fine, fixed-dose, triple combination inhaler Trimbow is more effective than Utibron (indacaterol and glycopyrronium) as a therapy for chronic obstructive pulmonary disease (COPD). Trimbow contains the anti-inflammatory inhaled corticosteroid (ICS) beclomethasone dipropionate and two bronchodilators, the long-acting beta2 agonist (LABA) formoterol fumarate and the…