News

CPAP Use May Lower COPD Flare Risk in Patients With Sleep Apnea

People with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) may experience fewer acute disease exacerbations if they regularly use noninvasive ventilation at night, a small study in Greece reported. “Good” nighttime use of continuous positive airway pressure (CPAP), a type of noninvasive ventilation, also aided lung…

Inflammatory Markers in Blood May Help ID COPD Outcomes Risk

Measuring inflammatory markers during routine blood tests in people with chronic obstructive pulmonary disease (COPD) could acute exacerbations at risk of experiencing worse outcomes, according to a small literature review study. Specifically, the researchers suggest measuring the neutrophil-to-lymphocyte ratio (NLR) — an indicator of systemic or body-wide inflammation. The…

Educating About Endobronchial Valves Is Aim of Collaboration

Pulmonx and the American Lung Association have partnered to educate patients and healthcare providers about treatment options, including endobronchial valves that can help people breathe easier who have severe emphysema, a form of chronic obstructive pulmonary disease (COPD). Led by the American Lung Association, the Treating Severe COPD…

AstraZeneca Acquires Global Rights to C4XD’s NRF2 Activator Program

AstraZeneca has acquired the exclusive rights to develop and commercialize C4X Discovery’s oral NRF2 activator for treating chronic obstructive pulmonary disease (COPD) and other inflammatory and respiratory diseases. The activator program aims to harness the antioxidant and anti-inflammatory properties of NRF2 in these conditions, although COPD will be…

Japan Approves Zephyr Valve for Severe Emphysema

Pulmonx has won the green light in Japan to market its Zephyr Endobronchial Valve, a bronchoscope-placed device designed to help people breathe easier who have severe emphysema, a form of chronic obstructive pulmonary disease (COPD). With the OK from the Japanese Ministry of Health, Labour and Welfare…

FDA OKs Phase 2 Clinical Trial of EP395 for COPD Patients

The U.S. Food and Drug Administration (FDA) has authorized EpiEndo Pharmaceuticals to conduct a Phase 2a clinical trial of its antibiotic treatment EP395 in people with chronic obstructive pulmonary disease (COPD). It will be the first test of the experimental therapy in COPD patients. The clinical trial…

Spinoff Breathe Biologics to Lead TSOI’s Stem Cell Therapy Research

Therapeutic Solutions International (TSOI) has launched a pharmaceutical spin-off — Breathe Biologics — that will take the lead in developing and marketing therapies for chronic obstructive pulmonary disease (COPD), including JadiCell, its investigational stem cell therapy. TSOI has licensed to Breathe Biologics the investigational new drug (IND) application for…

At-home Testing Kit for Alpha-1 Deficiency Wins FDA Clearance

AlphaID At Home, a screening kit to detect alpha-1-antitrypsin deficiency (alpha-1), has been cleared by the U.S. Food and Drug Administration (FDA). The free, direct-to-consumer screening kit developed by Grifols will enable adults in the U.S. to determine their genetic risk of developing lung or liver disease linked to…