JadiCells, the investigational stem cell therapy by Therapeutic Solutions International (TSOI), preserved lung function and increased the number of cells thought to have a role in lung repair in mice with inflammation-induced lung injury, the company announced. These preclinical findings further support the potential of JadiCells to both prevent…
The National Institutes of Health (NIH) has awarded Albany Medical College, in New York, a $2.8 million, five-year grant to study how carbon dioxide and metabolism impact people with chronic obstructive pulmonary disorder (COPD). COPD, affecting more than 16.4 million people in the U.S. alone, is a group of…
The U.S. Food and Drug Administration (FDA) will allow Sanolla’s VoqX to be used in the clinic, the first stethoscope that can be used to detect infrasounds — acoustic waves that humans cannot hear. The primary care stethoscope — a diagnostic tool clinicians normally use to listen to sounds…
Activating receptor proteins of prostaglandins (PGs) — fatty molecules with hormone-like effects — restores the regenerative potential of lung cells in cellular models of chronic obstructive pulmonary disease (COPD), a study shows. This was achieved with iloprost and misoprostol — two compounds that mimic the activity of PGs and are…
Patients with moderate-to-very severe chronic obstructive pulmonary disease (COPD) and frequent flare-ups who were given astegolimab, a medicine in Genentech’s pipeline, reported a better health-related quality of life than those taking a placebo, a study found. The findings are from a Phase 2a trial, called COPD-ST2OP (NCT03615040),…
Researchers in the U.S. have identified a new cell type in the narrowest airways of the lungs that, besides being involved in producing the mucus lining the airways, can give rise to alveolar epithelial type 2 (AT2) cells, which are involved in lung tissue repair and regeneration. This cell type,…
The levels of a mucus protein called MUC5AC — abnormally increased when a person gets a viral infection — are associated with airway inflammatory responses and exacerbation severity in people with chronic obstructive pulmonary disease (COPD), a study shows. Simply put, the increased mucus protein from viruses creates a “vicious…
Molecules called stapled peptides blocked the secretion, or release, of mucin proteins from airway cells and lessened mucus buildup in the lungs of mice in a study. According to its researchers, these findings led to the creation of an inhaled aerosol that was tested in the mice and, with further…
Older adults with chronic obstructive pulmonary disease (COPD) found the Wellinks health mobile app useful and valuable for managing the disease and treatment, a small pilot study suggests. According to study authors, the Wellinks platform may aid patient engagement and outcomes. “It’s exciting to see this population of chronically ill patients successfully…
Strados Labs has been awarded a $990,118 grant to advance the development of its RESP Smart Sensor Platform, a noninvasive wearable lung device to help in the early detection of chronic obstructive pulmonary disease (COPD) and other respiratory infectious conditions. The funds are part of a second phase…
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