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Even At Low Levels, Long-term Air Pollution May Increase COPD Risk

Long-term exposure to air pollution, even at relatively low concentrations, is associated significantly with reduced lung function and may increase the risk of chronic obstructive pulmonary disease (COPD), according to a population-based study in Canada. “Few studies have examined the relationship between air pollution and the lung health of adults…

TSOI Nets IND Number Ahead of Proposed JadiCell Clinical Trial

Note: This story was updated June 6, 2022, to note that the U.S. Food and Drug Administration has assigned an Investigational New Drug application (IND) number to Therapeutic Solutions International experimental JadiCell therapy. The FDA has not yet approved the company’s IND application. The U.S. Food and Drug Administration’s review…

Immune-suppressing Cells Boost JadiCells’ Therapeutic Effects in Mice

Treatment with immune-suppressing myeloid-derived suppressor cells alongside JadiCell — an investigational stem cell therapy from Therapeutic Solutions International (TSOI) for chronic obstructive pulmonary disease (COPD) — led to more significant reductions in lung damage in mice compared with either treatment alone. Using them together also enhanced pulmonary regeneration…

TSOI Seeks FDA OK to Launch Phase 1 Trial of JadiCell

Therapeutic Solutions International (TSOI) is seeking permission from the U.S. Food and Drug Administration (FDA) to conduct a Phase 1 study of JadiCell, its investigational stem cell therapy, in 10 people with advanced chronic obstructive pulmonary disease (COPD). The request — submitted in the form of an investigational…