Dupixent found to prevent COPD exacerbations in Phase 3 trial

Dupixent (dupilumab) — a medication initially approved for exzema — was found to significantly reduce the number of disease exacerbations and to improve lung function in people with chronic obstructive pulmonary disease (COPD), meeting the primary and key secondary goals of the pivotal Phase 3 BOREAS trial. A similarly…

CPAP Use May Lower COPD Flare Risk in Patients With Sleep Apnea

People with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) may experience fewer acute disease exacerbations if they regularly use noninvasive ventilation at night, a small study in Greece reported. “Good” nighttime use of continuous positive airway pressure (CPAP), a type of noninvasive ventilation, also aided lung…

Inhaled Ensifentrine Improves Lung Function, Phase 3 Trial Shows

Ensifentrine, Verona Pharma’s experimental inhalation therapy, safely and effectively improves lung function and reduces the rate and risk of exacerbations, or episodes of disease worsening, in people with moderate to severe chronic obstructive pulmonary disease (COPD). That is according to top-line, six-month data from the Phase 3 ENHANCE-2…

MgIG-Salmeterol Combo Fares Well in Rat Study

Salmeterol, combined with the root extract derivative magnesium isoglycyrrhizinate (MgIG), eased the signs and symptoms of chronic obstructive pulmonary disease (COPD) in rats, a study demonstrated. Salmeterol-MgIG combination therapy was more effective than the approved salmeterol-fluticasone combination in improving lung function and reducing inflammation. The researchers suggested…

Even At Low Levels, Long-term Air Pollution May Increase COPD Risk

Long-term exposure to air pollution, even at relatively low concentrations, is associated significantly with reduced lung function and may increase the risk of chronic obstructive pulmonary disease (COPD), according to a population-based study in Canada. “Few studies have examined the relationship between air pollution and the lung health of adults…

Wellinks’ Mobile App Easy to Use, Valuable for Managing COPD: Study

Older adults with chronic obstructive pulmonary disease (COPD) found the Wellinks health mobile app useful and valuable for managing the disease and treatment, a small pilot study suggests. According to study authors, the Wellinks platform may aid patient engagement and outcomes. “It’s exciting to see this population of chronically ill patients successfully…