News

A first-in-human clinical trial testing the safety and tolerability of EP395, EpiEndo Pharmaceuticals’ experimental treatment for chronic obstructive pulmonary disease (COPD), is now finished. EpiEndo is planning to launch a Phase 2a trial testing EP395 in people with COPD later this year. “The successful completion of this study…

Treatment with immune-suppressing myeloid-derived suppressor cells alongside JadiCell — an investigational stem cell therapy from Therapeutic Solutions International (TSOI) for chronic obstructive pulmonary disease (COPD) — led to more significant reductions in lung damage in mice compared with either treatment alone. Using them together also enhanced pulmonary regeneration…

Therapeutic Solutions International (TSOI) is seeking permission from the U.S. Food and Drug Administration (FDA) to conduct a Phase 1 study of JadiCell, its investigational stem cell therapy, in 10 people with advanced chronic obstructive pulmonary disease (COPD). The request — submitted in the form of an investigational…

The digital Kaia Health mobile app helped people with chronic obstructive pulmonary disease (COPD) to better adhere to a physical activity plan after completing an in-hospital pulmonary rehabilitation program, a study found. Moreover, the patients who used the application for six months also saw…

Researchers have developed a new genetic tool for predicting the risk of chronic obstructive pulmonary disease (COPD) in individuals of non-European ancestry. It was found to more effectively determine COPD risk for both African Americans and heavy smokers than existing models that are primarily built on genetic information from…

Among people with lung cancer who undergo tumor removal surgery, chronic obstructive pulmonary disease (COPD) is linked to a higher rate of postoperative pulmonary complications and longer hospital stays, including a greater need for intensive care unit (ICU) treatment, according to a large retrospective Australian study. A history of…

Lung-directed treatment with isthmin 1 (ISM1) — a soluble signaling molecule naturally present in the lungs — reduced lung inflammation, suppressed emphysema development, and preserved lung function in a mouse model of chronic obstructive pulmonary disease (COPD), a study shows. Emphysema is a severe form of COPD marked by damage…

Being exposed to pesticides at work increases the risk of developing chronic obstructive pulmonary disease (COPD), a large U.K.-based study has found. This was true regardless of whether people smoked or had asthma; smoking and asthma are both known risk factors for COPD. “Focused preventive strategies for workers exposed…

JadiCells, the investigational stem cell therapy by Therapeutic Solutions International (TSOI), preserved lung function and increased the number of cells thought to have a role in lung repair in mice with inflammation-induced lung injury, the company announced. These preclinical findings further support the potential of JadiCells to both prevent…

The National Institutes of Health (NIH) has awarded Albany Medical College, in New York, a $2.8 million, five-year grant to study how carbon dioxide and metabolism impact people with chronic obstructive pulmonary disorder (COPD). COPD, affecting more than 16.4 million people in the U.S. alone, is a group of…